Automatic Assessment of Ki-67 Proliferation Index in Lymphoma
نویسندگان
چکیده
منابع مشابه
Prognostic relevance of the Ki-67 proliferation index in patients with mantle cell lymphoma
BACKGROUND A high Ki-67 proliferation index (PI) in neoplastic cells is associated with poor survival in mantle cell lymphoma (MCL). We aimed to determine the cut-off values for the Ki-67 PI as a prognostic factor in MCL according to bone marrow findings. METHODS Immunohistochemical (IHC) staining for Ki-67 was performed on formalin-fixed paraffin-embedded biopsy tissues from 56 patients with...
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The proliferation indices (PIs) were determined in 33 meningiomas using two monoclonal antibodies to the Ki-67 antigen (Ki-67 and MIB1). PIs obtained using Ki-67 on frozen material were intermediate between the lowest and highest MIB1 PIs determined in paraffin wax sections. Preoperative embolisation did not influence Ki67 PI, but four of the 15 embolised tumours showed substantially increased ...
متن کاملImmunohistochemical evaluation of Ki-67, PCNA and MCM2 proteins proliferation index (PI) in advanced gastric cancer.
The current study objective was to assess the proliferation indices (PI) of Ki-67, PCNA and MCM2 proteins in advanced gastric cancer and in metastatic lymph node in correlation with certain clinicopathological features and with postoperative survival of patients. The study was conducted in a group of 100 patients with advanced gastric cancers. Involvement of local lymph nodes was present in 36 ...
متن کاملEvaluation of the Ki-67 Proliferation Index and Urocortin Expression in Women with Ovarian Endometriomas.
OBJECTIVE The reasons why endometriosis is more aggressive and invasive in some patients are unknown. Despite the importance of population-based clinically defined risk factors in the prediction of recurrence, biochemical markers obtained from the patient are more valuable for prediction on an individual basis. Therefore, the discovery of significant potential biomarkers could be useful to clin...
متن کاملThe relation between bone marrow angiogenesis and the proliferation index Ki-67 in multiple myeloma.
AIM Angiogenesis correlates with disease progression in various haematological malignancies. This study investigated the association between microvascular density (MVD) and the Ki-67 proliferation index (Ki-67 PI), bone marrow infiltration, and C reactive protein (CRP) in patients with multiple myeloma. METHODS Bone marrow MVD was examined in 44 biopsies at diagnosis and 15 in plateau phase b...
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ژورنال
عنوان ژورنال: Iranian Journal of Radiology
سال: 2019
ISSN: 1735-1065,2008-2711
DOI: 10.5812/iranjradiol.99143